Author: Vinita Yadav, Ph.D.
Editors: Callie Corsa, Zena Lapp, and Noah Steinfeld
Molds or fungi are generally known for their pathogenic properties, but they are also used in the food and pharmaceutical industries. We can find several examples of uses in our daily lives including yeast used in brewing and baking, Aspergillus species used in making Soy sauce, and Penicillium species used in cheese industries. Penicillium species also make antibiotics like Penicillin.
During my thesis, my project was to search for fungi which produce alpha-L-Rhamnosidase, an enzyme that cuts the terminal L-rhamnose from several glycosylated compounds: compounds that have sugar attached. L-rhamnose is sweet in taste but not found in nature in its free form. It is always attached to several other biomolecules from lipid/fat molecules to proteins to other metabolites like flavonoids, steroids, or terpenoids (Figure 1).