Induced stem cell power: The power to reset a cell’s career path

By Shirley Lee

Featured image: Induced pluripotent stem cells stained red, their nuclei are stained blue. Source.

When I was first taught the process of embryonic development in biology class back in high school, I was amazed by the complexity of the process. Each one of us was derived from a single cell (the result of the joining of an egg and a sperm), which then went through countless cell divisions. It amazes me that something so small is packed with so much biological potential!

Naturally, scientists set out to get to the bottom of this phenomenon. In the 1990s, people discovered how to extract these cells (called stem cells) from developing human embryos in order to study the process underlying stem cell development in research laboratories. Continue reading “Induced stem cell power: The power to reset a cell’s career path”

Science behind-the-scenes: (Almost) Everything grade school taught you about science is wrong

By Belle Moyers

Do you remember being taught the “Scientific Method” in school? There were always slight variations, but it went something like:

  1. Ask a question
  2. Do background research
  3. Form an educated guess (hypothesis)
  4. Test your hypothesis by doing an experiment
  5. Analyze your data and draw a conclusion
  6. If your hypothesis is wrong, return to step 3 with a new hypothesis.
  7. Communicate your results

These steps seem like a great tool to introduce students to science.  They’re simple and easy to understand once the teacher explains words like “hypothesis” and “experiment”.  If you’re like me, perhaps you remember it seeming straightforward—scientists follow a linear set of steps that produce powerful results. Teachers drilled that method into us grade after grade.  If only they weren’t completely wrong.

Continue reading “Science behind-the-scenes: (Almost) Everything grade school taught you about science is wrong”

Escaping the bunker mentality, part II…

By Kirsti Ashworth

Last week, I introduced the process of transdisciplinary research: an iterative, co-operative approach that brings communities and researchers together to collaborate at all stages of the research process. But given the difficulties of finding funding for traditional scientific research, can this kind of research become a reality? There are plenty of examples out there that suggest it can.

There are already signs of change: many scientists are starting to consider the practical implications and applications of their research, looking beyond the narrow confines of their discipline, and engaging with local stakeholders. International institutes, science co-ordinators, and funding agencies are actively promoting inter- and transdisciplinary research. The field of sustainability is a prime example. Continue reading “Escaping the bunker mentality, part II…”

Escaping the bunker mentality

By Kirsti Ashworth

Save the date! 2016 is the Year of the Future.

A future that’s bright, a future that’s transdisciplinary…

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Image credit: Arnaud Bouissou/MEDDE/SG COP21

On December 13th 2015, the world’s leaders reached a rare consensus and ratified an historic accord designed to limit climate change to 2°C. January 1st 2016 marked the official launch of the UN’s Sustainable Development Goals and the start of the next Assessment Report for the IPCC. These events have shifted the emphasis from investigating and reporting the physical science behind the unprecedented changes we’re seeing on our planet to identifying and implementing strategies to avoid further change (mitigation) or to minimize their impacts (adaptation).

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The budding brain: How yeast give rise to treatments for neurodegenerative diseases

By Sara Wong

What do humans and baker’s yeast have in common? Surprisingly, they share a massive amount of genetic information and are governed by many of the same cellular processes. Although yeast do not have organs or limbs, they work like human cells and can be used to study a wide range of human diseases. Yeast are cheap, grow quickly, and are easily manipulated. These qualities allow scientists who study yeast to discover new genes and pathways relatively easily compared to other model organisms, like mice. One area of yeast research focuses on understanding neurodegenerative diseases, such as Parkinson’s and Alzheimer’s disease.

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How fireflies illuminated our understanding of the world

By Noah Steinfeld

In the early 1950s at Johns Hopkins University, William E. McElroy, a young professor, wanted to figure out what makes fireflies glow. He would pay a quarter to children in the Baltimore area for every 100 fireflies they brought him. McElroy was regarded as a curiosity in the community: the stereotype of an eccentric scientist. But what these people didn’t know was that as a result of this research, McElroy would one day create a tool that would revolutionize the way scientists do biological research.

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