Author: Ada Hagan
Editors: Alisha John, Scott Barolo
As we discussed last time, bacteria that infect the human body face a major challenge: iron, which is essential for bacterial growth, is hard to obtain from human tissues. Many pathogenic bacteria solve this problem by deploying “stealth siderophores,” which steal iron from human iron-binding proteins while evading our defenses. In the battle between humans and pathogenic bacteria, our best weapons, antibiotics, are being weakened by widespread resistance. Is there a way to use bacteria’s need for iron against them?
Continue reading “Spinach and siderophores, part 2: Getting the upper hand”

Almost 100 years ago, the English biologist and statistician Dr. Ronald Fisher was enjoying a cup of tea with his Cambridge University colleagues when another biologist, Dr. Muriel Bristol, made an interesting claim. Bristol asserted that just by tasting her tea, she could infer whether the tea was poured into the cup before the milk, or the milk before the tea.